AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats-Reference-Cited by-同舟云学术

AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats

Published:2009-12 Issue:7 Volume:55 Page:529-535
ISSN:0197-0186
Container-title:Neurochemistry International
language:en
Short-container-title:Neurochemistry International

Author:

Kanemaru Kazuya,Nishi Kyoko,Diksic Mirko

Publisher

Elsevier BV

Subject

Cell Biology,Cellular and Molecular Neuroscience

Reference61 articles.

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4. The increase an brainstem tryptophan hydroxylase (TRPH) activity induced depolarization (DEP) or phosphorylating conditions is blocked by 3(3-methoxyphenyl)-3-(3-dimethylaminopropyl)-4,4-dimethylpiperidine-2,6-dione (AGN2979);Boadle-Biber,1982

5. Activation of tryptophan hydroxylase by stimulation of central serotonergic neurons;Boadle-Biber;Biochem. Pharmacol.,1983

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2. The Flinders Sensitive Line Rat Model of Depression—25 Years and Still Producing;Pharmacological Reviews;2013-01

3. Neurochemical and Behavioural Changes in Rat Models of Depression;Croatica Chemica Acta;2011

4. Toward a better understanding of depression and anxiety. The importance of tryptophan hydroxylase activation blockade: The origin of a unique anxiolytic antidepressant;Drug Development Research;2010-09-15