Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands
Author:
Funder
Canadian Institutes of Health Research
Publisher
Elsevier BV
Subject
Multidisciplinary
Reference70 articles.
1. In glaucoma the upregulated truncated TrkC.T1 receptor isoform in glia causes increased TNF-alpha production, leading to retinal ganglion cell death;Bai;Invest. Ophthalmol. Vis. Sci.,2010
2. Protein folding in the endoplasmic reticulum;Braakman;Cold Spring Harb Perspect. Biol.,2013
3. A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist;Brahimi;Biochim. Biophys. Acta,2010
4. The paradoxical signals of two TrkC receptor isoforms supports a rationale for novel therapeutic strategies in ALS;Brahimi;PLoS One,2016
5. The EGF receptor family: spearheading a merger of signaling and therapeutics;Bublil;Curr. Opin. Cell Biol.,2007
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor;Molecular Pharmacology;2021-08-31
2. Delayed onset of inherited ALS by deletion of the BDNF receptor TrkB.T1 is non-cell autonomous;Experimental Neurology;2021-03
3. Evaluation of Pharmacokinetic Properties, Toxicity, and Bioactive Cytotoxic Activity of Black Rice (Oryza sativa L.) as Candidates for Diabetes Mellitus Drugs by in silico;Biointerface Research in Applied Chemistry;2021-01-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3