CDK12 regulates co-transcriptional splicing and RNA turnover in human cells
Author:
Funder
National Cancer Institute
Rogel Cancer Center, University of Michigan
NIH
National Human Genome Research Institute
Publisher
Elsevier BV
Subject
Multidisciplinary
Reference67 articles.
1. Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain;Ameur;Nat. Struct. Mol. Biol.,2011
2. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks;Aymard;Nat. Struct. Mol. Biol.,2014
3. Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity;Bajrami;Cancer Res.,2014
4. Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex;Bartkowiak;J. Biol. Chem.,2015
5. CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1;Bartkowiak;Genes Dev.,2010
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