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A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart

  • Published:2023-08 Issue:8 Volume:26 Page:107283
  • ISSN:2589-0042
  • Container-title:iScience
  • language:en
  • Short-container-title:iScience

Author:

Angelini AudeORCID,Trial JoAnn,Saltzman Alexander B.,Malovannaya Anna,Cieslik Katarzyna A.ORCID

Funder

Curtis and Doris K. Hankamer Foundation

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health

Medtronic Foundation

National Institute on Aging

National Institutes of Health Office of the Director

Cancer Prevention and Research Institute of Texas

National Cancer Institute

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference105 articles.

1. Extracellular matrix (ECM) microstructural composition regulates local cell-ECM biomechanics and fundamental fibroblast behavior: a multidimensional perspective;Pizzo;J. Appl. Physiol.,2005

2. Molecular imaging of the cardiac extracellular matrix;de Haas;Circ. Res.,2014

3. Cardiac fibroblasts and the extracellular matrix in regenerative and nonregenerative hearts;Hortells;J. Cardiovasc. Dev. Dis.,2019

4. Fibroblasts: The arbiters of extracellular matrix remodeling;DeLeon-Pennell;Matrix Biol.,2020

5. Extracellular matrix directs phenotypic heterogeneity of activated fibroblasts;Avery;Matrix Biol.,2018

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