PDZD8-deficient mice accumulate cholesteryl esters in the brain as a result of impaired lipophagy

Author:

Morita Keiko,Wada Mariko,Nakatani Kohta,Matsumoto Yuki,Hayashi Nahoki,Yamahata Ikuko,Mitsunari Kotone,Mukae Nagi,Takahashi Masatomo,Izumi Yoshihiro,Bamba Takeshi,Shirane MichikoORCID

Publisher

Elsevier BV

Subject

Multidisciplinary

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3. Cholesterol metabolism is a druggable Axis that independently regulates tau and amyloid-beta in iPSC-derived alzheimer's disease neurons;van der Kant;Cell Stem Cell,2019

4. Amyloid-beta-independent regulators of tau pathology in Alzheimer disease;van der Kant;Nat. Rev. Neurosci.,2020

5. TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge;Nugent;Neuron,2020

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