Next-generation repeat-free FISH probes for DNA amplification in glioblastoma in vivo: Improving patient selection to MDM2-targeted inhibitors-Reference-Cited by-同舟云学术

Next-generation repeat-free FISH probes for DNA amplification in glioblastoma in vivo: Improving patient selection to MDM2-targeted inhibitors

Published:2017-01 Issue: Volume:210 Page:28-33
ISSN:2210-7762
Container-title:Cancer Genetics
language:en
Short-container-title:Cancer Genetics

Author:

Brunelli Matteo,Eccher Albino,Cima Luca,Trippini Tobia,Pedron Serena,Chilosi Marco,Barbareschi Mattia,Scarpa Aldo,Pinna Giampietro,Cabrini Giulio,Pilotto Sara,Carbognin Luisa,Bria Emilio,Tortora Giampaolo,Fioravanzo Adele,Schiavo Nicola,Meglio Mario,Sava Teodoro,Belli Laura,Martignoni Guido,Ghimenton Claudio

Publisher

Elsevier BV

Subject

Cancer Research,Genetics,Molecular Biology

Reference13 articles.

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2. The MDM2 inhibitor AMG 232 demonstrates robust antitumor efficacy and potentiates the activity of p53-inducing cytotoxic agents;Canon;Mol Cancer Ther,2015

3. MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways;Saiki;Oncotarget,2014

4. Preclinical efficacy of the MDM2 inhibitor RG7112 in MDM2 amplified and TP53 wild-type glioblastomas;Verreault;Clin Cancer Res,2015

5. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment;Zhao;J Med Chem,2015

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1. MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma;Journal of Clinical Pathology;2020-11-03

2. Mutational game changer: Chromothripsis and its emerging relevance to cancer;Mutation Research/Reviews in Mutation Research;2018-07