Cholesterol retention in Alzheimer's brain is responsible for high β- and γ-secretase activities and Aβ production
Author:
Publisher
Elsevier BV
Subject
Neurology
Reference63 articles.
1. Neuronal membrane cholesterol loss enhances amyloid peptide generation;Abad-Rodriguez;J. Cell Biol.,2004
2. Protection by cholesterol-extracting cyclodextrins: a role for N-methyl-d-aspartate receptor redistribution;Abulrob;J. Neurochem.,2005
3. Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux;Akiyama;Mol. Cell. Biol.,2002
4. Brain cholesterol: long secret life behind a barrier;Bjorkhem;Arterioscler. Thromb. Vasc. Biol.,2004
5. Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein;Cordy;Proc. Natl. Acad. Sci. U. S. A.,2003
Cited by 226 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Converged avenues: depression and Alzheimer’s disease– shared pathophysiology and novel therapeutics;Molecular Biology Reports;2024-01-28
2. Sex-dependent effect of sublethal copper concentrations on de novo cholesterol synthesis in astrocytes and their possible links to variations in cholesterol and amyloid precursor protein levels in neuronal membranes;Biology of Sex Differences;2024-01-08
3. Cholesterol and oxysterols in retinal neuron-glia interactions: relevance for glaucoma;Frontiers in Ophthalmology;2024-01-03
4. Flavonoids and fibrate modulate apoE4-induced processing of amyloid precursor protein in neuroblastoma cells;Frontiers in Neuroscience;2023-12-22
5. Lipids and lipoproteins may play a role in the neuropathology of Alzheimer’s disease;Frontiers in Neuroscience;2023-11-16
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3