A sensitive and rapid ultra HPLC–MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma-Reference-Cited by-同舟云学术

A sensitive and rapid ultra HPLC–MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma

Published:2012-01 Issue: Volume:880 Page:132-139
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Peer Cody J.,Spencer Shawn D.,VanDenBerg Dustin A.H.,Pacanowski Michael A.,Horenstein Richard B.,Figg William D.

Funder

National Institutes of Health

National Institute of General Medicine Science

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference24 articles.

1. Clopidogrel for the secondary prevention of stroke

2. Clopidogrel resistance caused by a failure to metabolize clopidogrel into its metabolites

3. Structure and Stereochemistry of the Active Metabolite of Clopidogrel

4. Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

5. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel

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