Screening and identiﬁcation of the main metabolites of 2-amino-9H-pyrido[2,3-b]indole (AαC) in liver microsomes and rat urine by using UPLC-Q-TOF-MS/MS-Reference-Cited by-同舟云学术

Screening and identiﬁcation of the main metabolites of 2-amino-9H-pyrido[2,3-b]indole (AαC) in liver microsomes and rat urine by using UPLC-Q-TOF-MS/MS

Published:2017-03 Issue: Volume:1046 Page:110-121
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Hu Kai,Zhao Ge,Fu Yufeng,Wang Sheng,Yuan Hang,Xie Fuwei,Zhang Shusheng,Liu Huimin,Liu Minying

Funder

National Nature Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference33 articles.

1. Formation and biochemistry of carcinogenic heterocyclic aromatic amines in cooked meats;Turesky;Toxicol. lett.,2007

2. Effect of Thermal Treatments on the Formation of Heterocyclic Aromatic Amines in Various Meats;Raza;J. Food Process. Pres.,2015

3. Metabolism and Biomarkers of Heterocyclic Aromatic Amines in Molecular Epidemiology Studies: Lessons Learned from Aromatic Amines;Turesky;Chem. Res. in Toxicol.,2011

4. Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2, 3-b]indole (MeA(C) and 2-amino-9H-pyrido[2, 3-b]indole (AαC) and identification of DNA adducts in organs from rats dosed with MeAαC;Frederiksen;Carcinogenesis,2004

5. Exposure to (-carbolines norharman and harman;Pfau;J. Chromatogr. B,2004

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3. Effects of 2-amino-9H-pyrido[2,3-b]indole (AαC) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells;Toxicology Mechanisms and Methods;2017-11-28