1. 1School of Chemistry, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
2. 2Manchester Institute of Biotechnology, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
3. 3Firsway Health Centre, 121 Firs Way, Sale, Manchester M33 4BR, UK
4. 4Faculty of Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK
5. †Present address: Department of Biochemistry, Institute of Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Crown St, Liverpool L69 7ZB, UK.