Elastase and elastase inhibitor from Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger-Reference-Cited by-同舟云学术

Elastase and elastase inhibitor from Aspergillus fumigatus, Aspergillus flavus and Aspergillus niger

Published:2004-05-01 Issue:5 Volume:53 Page:351-354
ISSN:0022-2615
Container-title:Journal of Medical Microbiology
language:en
Short-container-title:

Author:

Okumura Yoshiyuki¹,Ogawa Kenji¹,Nikai Toshiaki¹

Affiliation:

1. Department of Quality Control, Mathuurayakugyo Co. Ltd, 24-21 Enjo-chou, Syowa-ku, Nagoya 466-0054, Japan 2Department of Microbiology, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tenpaku-ku, Nagoya 468-8503, Japan 3Department of Pulmonary Medicine, National Higashinagoya Hospital, 5-101 Umemorizaka, Meito-ku, Nagoya 465-8620, Japan

Abstract

Elastolytic and elastase inhibitory activities were investigated for 13 strains ofAspergillus fumigatus, three strains ofAspergillus flavusand three strains ofAspergillus niger. Nine of the 13 strains ofA. fumigatusand all strains ofA. flavusdemonstrated elastase activity (more than 1 unit ml−1). Six of the 13 strains ofA. fumigatusand all strains ofA. flavusexpressed elastase inhibitory activity (more than 2 units ml−1). However, no elastase or elastase inhibitory activities were observed withA. niger. It was also found that crude elastase inhibitors from six strains ofA. fumigatusand two strains ofA. flavuswere stable to heat treatment at 100 °C for 10 min. In addition, human leukocyte elastases were inhibited by crude elastase inhibitors fromA. fumigatusandA. flavus; however, no effect was observed on the elastase derived from porcine pancreas.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

Reference21 articles.

1. Correlation between the elastase activity index and invasiveness of clinical isolates of Aspergillus fumigatus;Blanco;J Clin Microbiol,2002

2. Lack of vessel wall elastolysis in human invasive pulmonary aspergillosis;Denning;Infect Immun,1992

3. Purification and properties of elastase from Aspergillus fumigatus;Frosco;Infect Immun,1992

4. The effect of elastase-specific monoclonal and polyclonal antibodies on the virulence of Aspergillus fumigatus in immunocompromised mice;Frosco;Mycopathologia,1994

5. Elastase activity from Aspergillus species and inhibition by urinastatin;Hasegawa;Jpn J Med Mycol,1994

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