Correlation between the Elastase Activity Index and Invasiveness of Clinical Isolates of Aspergillus fumigatus-Reference-Cited by-同舟云学术

Correlation between the Elastase Activity Index and Invasiveness of Clinical Isolates of Aspergillus fumigatus

Published:2002-05 Issue:5 Volume:40 Page:1811-1813
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Blanco Jose L.¹,Hontecillas Raquel¹,Bouza Emilio²,Blanco Isabel¹,Pelaez Teresa²,Muñoz Patricia²,Perez Molina Jose²,Garcia Marta E.¹

Affiliation:

1. Departamento Patología Animal I, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid

2. Servicio do Microbiologia Clinica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain

Abstract

ABSTRACT We calculated an elastase activity index (EAI) by dividing the diameter of the elastin lysis halo by the fungal growth diameter. After 10 days' incubation at 37°C, all strains but one obtained from invasive aspergillosis showed an EAI ≥ 1. Of the 18 strains obtained from colonized patients, only 4 (22.2%) had an EAI ≥ 1, whereas neither of the strains isolated from patients with fungus ball reached this value. Overall, 44 out of the 142 strains obtained from the environment had an EAI ≥ 1 (30.9%).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.5.1811-1813.2002

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