Abstract
In addition to monocrotaline, retronecine N-oxide and three new alkaloids, retusine,
retusamine, and an incompletely characterized base, m.p. 130-132°C, have been isolated
from Crotalaria retusa L. The proportion of alkaloid occurring as N-oxide varied
from 2 to 70 per cent. in different plant specimens. Hxdrolysis of retusine gives 2,3,4-
trimethyl-4-hydroxyglutaric acid 1,4-lactone (dihydroanhydromonocrotalic acid) and
an amino alcohol, C8H15O2N, probably hastanecine.
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