Involvement of astrocytic CYP1A1 isoform in the metabolism and toxicity of the alkaloid pyrrolizidine monocrotaline

Author:

Nascimento Ravena P.,Oliveira Joana L.,Carvalho José Leilton C.,Santos William A.,Pires Thyago Rubens C.,Batatinha Maria José M.,El-Bachá Ramon S.,Silva Victor Diógenes A.,Costa Silvia L.ORCID

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fundação de Aparo à pesquisa do Estado da Bahia (FAPESB)

Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Programa de Pós-graduação em Ciência Animal nos Trópicos

Publisher

Elsevier BV

Subject

Toxicology

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3. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples;Baker;Anal. Biochem.,1990

4. O alcalóide monocrotalina, extraído de Crotalaria retusa, altera a expressão de GFAP, a morfologia e o crescimento de culturas primárias de astrócitos;Barreto;Rev. Bras. Saúde Prod. Anim.,2006

5. Monocrotaline pyrrol is cytotoxic and alters the patterns of GFAP expression on astrocyte primary cultures;Barreto;Toxicol. In Vitro,2008

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