Determination of Enantiomeric Excess in Deuterated Chiral Hydrocarbons by Vibrational Circular Dichroism Spectroscopy-Reference-Cited by-同舟云学术

Determination of Enantiomeric Excess in Deuterated Chiral Hydrocarbons by Vibrational Circular Dichroism Spectroscopy

Published:1990-02 Issue:2 Volume:44 Page:235-238
ISSN:0003-7028
Container-title:Applied Spectroscopy
language:en
Short-container-title:Appl Spectrosc

Author:

Spencer Kevin M.¹,Cianciosi Steven J.¹,Baldwin John E.¹,Freedman Teresa B.¹,Nafie Laurence A.¹

Affiliation:

1. Department of Chemistry, Syracuse University, Syracuse, New York 13244-4100

Abstract

An improved procedure using vibrational circular dichroism spectroscopy for high-precision determinations of enantiomeric excess (ee) in chiral samples is described. Chiral trans-dideuteriocyclopropane is employed in the gas phase for percent ee measurements. This molecule is a member of the class of simple hydrocarbons made chiral by virtue of isotopic substitution for which no convenient and accurate alternative method of percent ee measurement is available. Percent ee determinations to within 1% are demonstrated for several ee values with and without contamination by the achiral cis-dideuteriocyclopropane species.

Publisher

SAGE Publications

Subject

Spectroscopy,Instrumentation

Link

http://journals.sagepub.com/doi/pdf/10.1366/0003702904085651

Reference9 articles.

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3. Synchronous double rotation in the stereomutation of optically active 1-phenylcyclopropane-2-d

4. A test for "wrong-bond" rupture in the thermal structural isomerization of phenylcyclopropane and a confirmation of the two-center epimerization mechanism in its stereomutation

5. Thermolysis of (1R,2R)-1,2-dideuteriocyclobutane. An application of vibrational circular dichroism to kinetic analysis

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