Development of dental varnish based on red propolis for the treatment and prevention of dental caries

Abstract

Caries is one of the most common chronic diseases in the world. To control and prevent the disease, it is important to expand the treatment options. The various types of propolis have been studied as alternatives. Studies have shown that Brazilian red propolis has important activity against S. mutans, as well as good anti-inflammatory activity. For the effective use of this alternative, it is necessary to develop pharmaceutical forms that make it feasible to handle and apply them. This study aims to produce a dental varnish based on red propolis, for later application in in vitro and in vivo studies. It is hoped that the formulation produced will conserve the good antimicrobial and anti-inflammatory activity of propolis and that it will be able to generate an innovative product for depositing patents with the National Institute of Industrial Property (INPI).