A new method to measure muscle protein synthesis in humans by endogenously introduced d9-leucine and using blood for precursor enrichment determination
Author:
Affiliation:
1. Center for Metabolic and Vascular Biology; Arizona State University; Tempe Arizona USA
2. Mayo Clinic in Arizona; Scottsdale Arizona USA
Funder
NIH/NIDDK
National Center for Advancing Translational Sciences
Publisher
Wiley
Subject
Physiology (medical),Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.12479/fullpdf
Reference33 articles.
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2. Metabolic labeling of proteins for proteomics;Beynon;Mol. Cell Proteomics,2005
3. Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study;Bohe;J. Physiol.,2003
4. Infusion of labeled KIC is more accurate than labeled leucine to determine human muscle protein synthesis;Chinkes;Am. J. Physiol.,1996
5. Mechanism of insulin's anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures;Chow;Am. J. Physiol. Endocrinol. Metab.,2006
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