Effect of tidal volume and positive end-expiratory pressure on expiratory time constants in experimental lung injury

Author:

Henderson William R.12,Dominelli Paolo B.2,Molgat-Seon Yannick2,Lipson Rachel3,Griesdale Donald E. G.14,Sekhon Mypinder1,Ayas Najib1,Sheel A. William2

Affiliation:

1. Division of Critical Care Medicine; Department of Medicine; Faculty of Medicine; University of British Columbia; Vancouver British Columbia Canada

2. School of Kinesiology; University of British Columbia; Vancouver British Columbia Canada

3. Emmes Canada; Burnaby British Columbia Canada

4. Department of Anesthesiology, Pharmacology & Therapeutics; University of British Columbia; Vancouver British Columbia Canada

Funder

VGH & UBC Hospital Foundation Best of Health Fund

University of British Columbia

Natural Science and Engineering Research Council

Publisher

Wiley

Subject

Physiology (medical),Physiology

Reference34 articles.

1. Expiratory flow-volume curves in mechanically ventilated patients with chronic obstructive pulmonary disease;Aerts;Acta Anaesthesiol. Scand.,1999

2. Flow and volume dependence of respiratory system mechanics during constant flow ventilation in normal subjects and in adult respiratory distress syndrome;Auler;Crit. Care Med.,1990

3. A simple method for assessing the validity of the esophageal balloon technique;Baydur;Am. Rev. Respir. Dis.,1982

4. Simple method to measure total expiratory time constant based on the passive expiratory flow-volume curve;Brunner;Crit. Care Med.,1995

5. Changes in lung composition and regional perfusion and tissue distribution in patients with ARDS;Dakin;Respirology,2011

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