Effects of a 217‐km mountain ultramarathon on the gut microbiota of an obese runner: A case report-Reference-Cited by-同舟云学术

Effects of a 217‐km mountain ultramarathon on the gut microbiota of an obese runner: A case report

Published:2024-08 Issue:16 Volume:12 Page:
ISSN:2051-817X
Container-title:Physiological Reports
language:en
Short-container-title:Physiological Reports

Author:

Saragiotto Giulio Kai¹^ORCID,de Oliveira Luiz Felipe Valter²^ORCID,Scharlack Nayara Kastem¹^ORCID,de Oliveira Milena Merizzi¹^ORCID,Freire Fernanda Campos³^ORCID,Simabuco Fernando Moreira¹⁴^ORCID,Sivieri Katia³^ORCID,Sartoratto Adilson⁵^ORCID,Belli Taisa¹⁶^ORCID,Antunes Adriane Elisabete Costa¹^ORCID

Affiliation:

1. Faculdade de Ciências Aplicadas Universidade Estadual de Campinas (FCA/UNICAMP) Limeira São Paulo Brazil

2. Department of Biotechnologies BiomeHub Florianópolis Santa Catarina Brazil

3. School of Pharmaceutical Sciences, State University of São Paulo “Júlio de Mesquita Filho” (UNESP) Araraquara São Paulo Brazil

4. Departamento de Bioquímica Universidade Federal de São Paulo (UNIFESP) São Paulo São Paulo Brazil

5. Centro Pluridisciplinar de Pesquisas Químicas Biológicas e Agrícolas, Universidade Estadual de Campinas (CPQBA/UNICAMP) Paulínia São Paulo Brazil

6. Departamento de Ciências do Esporte Faculdade de Educação Física, Universidade Estadual de Campinas (FEF/UNICAMP) Campinas São Paulo Brazil

Abstract

AbstractObesity is characterized by specific changes in the composition of the gut microbiota (GM). Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single‐stage mountain ultramarathon (MUM) with a mileage of 217 km. Fecal samples were collected 7 days before the race (T0), 15 min after the end of the race (T1), and 7 days after the end of the race (T2). GM composition was analyzed by real‐time PCR and shotgun sequencing. We observed a decrease in Bacillota/Bacteroidota ratio and α‐diversity after the race. After the 217‐km MUM, we observed a decrease in symbiont microorganisms and a notable increase in harmful bacteria. In conclusion, we found that the 217‐km MUM may have contributed to the intestinal dysbiosis of the obese runner.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas

Publisher

Wiley

Link

https://physoc.onlinelibrary.wiley.com/doi/pdf/10.14814/phy2.70017

Reference37 articles.

1. The effects of sustained fitness improvement on the gut microbiome: A longitudinal, repeated measures case‐study approach

2. Trimmomatic: a flexible trimmer for Illumina sequence data

3. Gut Microbiota in Nutrition and Health with a Special Focus on Specific Bacterial Clusters