Oral and intravenous pharmacokinetics of taurine in sprague-dawley rats: the influence of dose and the possible involvement of the proton-coupled amino acid transporter, PAT1, in oral taurine absorption-Reference-Cited by-同舟云学术

Oral and intravenous pharmacokinetics of taurine in sprague-dawley rats: the influence of dose and the possible involvement of the proton-coupled amino acid transporter, PAT1, in oral taurine absorption

Published:2017-10 Issue:19 Volume:5 Page:e13467
ISSN:2051-817X
Container-title:Physiological Reports
language:en
Short-container-title:Physiol Rep

Author:

Nielsen Carsten Uhd¹^ORCID,Bjerg Maria¹,Ulaganathan Nithiya¹,Holm René²

Affiliation:

1. Department of Physics, Chemistry and Pharmacy; University of Southern Denmark; Odense M Denmark

2. Pharmaceutical Science and CMC Biologics; H. Lundbeck A/S; Valby Denmark

Publisher

Wiley

Subject

Physiology (medical),Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.14814/phy2.13467/fullpdf

Reference26 articles.

1. H+/amino acid transporter 1 (PAT1) is the imino acid carrier: an intestinal nutrient/drug transporter in human and rat;Anderson;Gastroenterology,2004

2. Taurine uptake across the human intestinal brush-border membrane is via two transporters: H + -coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6);Anderson;J. Physiol.,2009

3. Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol;Broberg;Br. J. Pharmacol.,2012

4. Taurine, energy drinks, and neuroendocrine effects;Caine;Cleve. Clin. J. Med.,2016

5. Role of caloric content on gastric emptying in humans;Calbet;J. Physiol.,1997

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