The factors inflyencing the diffusion capacity of the lung in patients with myocardial infarction.

Abstract

The purpose of the study was to assess the factors associated with impaired lung diffusion capacity among the patients with STEMI. Material and methods. 107 patients with STEMI were included. Echocardiography, spirometry, body plethysmography, diffusion capacity of the lungs, laboratory indices of inflammatory status and myocardial dysfunction were performed on the 10-12 days of the hospital admission. 100 (93,4%) patients underwent percutaneous coronary intervention with stenting. Results. In the 1st group were included 59 (55,1%) patients with a normal diffusing lung capacity, in the 2nd group - 48 (44,9%) patients with reduced diffusing lung capacity (<80%). Patients of the 2nd group showed lower values of FEF75%, the increase of the end systolic volume LV, right and left atrial volume, and the increase concentrations of CRP in blood plasma. The discriminant analysis identified the factors affecting the decrease in DLCO. Conclusion. The factors associated with impaired lung diffusion capacity among the patients with STEMI are the following: age, maximum expiratory flow at the level of distal bronchi, the volume of the left atrial and the concentration of C-reactive protein, assessed on the 10th day of the disease.