THE HUMAN LECTIN SUPERSYSTEMS POSSESSING PROBIOTIC AND PROTECTIVE ACTIONS

Author:

Lakhtin M. V.1ORCID,Lakhtin V. M.1ORCID,Mironov A. Yu.1ORCID,Aleshkin V. A.1ORCID,Afanasiev S. S.1ORCID

Affiliation:

1. G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology

Abstract

The potential of useful for human immunobiological supersystems of lectins (SSL) recognizing carbohydrates and glycoconjugates of molecular or supramolecular protein/(oligo)peptide-containing constituents of biotopes is described. SSL recognize, reversibly bind, delivery to biotopes, orient natural or synthetic polymeric, polyvalent glycoconjugates (imitators of natural glycopolymers) at the cell surface. The key features of SSL are indicated and described. The possibilities of application and prospects of SL of probiotics, complement C4 system and protein hormones (on example of erythropoietins) in prognostics and diagnostics of pathologies, prophylaxis and therapy of diseases and medical biotechnology are evaluate

Publisher

EKOlab

Subject

Biochemistry, medical,Medical Laboratory Technology,General Medicine

Reference56 articles.

1. Lakhtin V.M., Lakhtin M.V., Aleshkin V.A., Afanasiev S.S. Identification of protein and lectin systems of erythropoietins.Ural´skiy nauchnyi vestnik. 2019; 2(1): 3-13. (in Russian)

2. Lakhtin V.M., Lakhtin M.V., Afanasiev S.S., Karaulov A.V., Aleshkin V.A., Afanasiev M.S. Glycoconjugates in chemiluminescent functional mapping immune sandwich against protein forms. Zdorov´e I obrazovanie v XXI veke. 2014; 16(4): 40-2.

3. Lakhtin M.V. Variants of isotyping the human complement component C4. Dis… Moscow; 2008. (in Russian)

4. Lakhtin M.V., Lakhtin V.M., Afanasiev S.S., Aleshkin A.V., Aleshkin V.A. Multipapameter detection and diagnostics of human erythropoietin. Elektronnyi zhurmal «Zdorov´e I obrazovanie v XXI veke». 2013; 15(2): 23-5. (in Russian)

5. Lakhtin M.V., Afanasiev S.S., Lakhtin V.M., Bajrakova A.L., Aleshkin V.A. The human probiotic bacteria lectins prevent spread of the mixed mycobiofilms «Candida+Aspergillus» of the human urogenital biotope mycobiota. Uspekhi meditsinskoy mikologii. 2014; 12: 34-7. (in Russian)

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1. The Potential of Lectins and their Recognized Glycoconjugates in the Human Body;Успехи современной биологии;2024-08-13

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