The Potential of Lectins and their Recognized Glycoconjugates in the Human Body

Author:

Lakhtin M. V.1,Lakhtin V. M.1,Mironov A. Yu.1,Aleshkin V. A.1,Afanasyev S. S.1,Kombarova S. Yu.1

Affiliation:

1. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Rospotrebnadzor

Abstract

The modern concepts of lectins and glycoconjugates binding to them, the features and patterns of their interaction, the protective role and potential in the human body are summarized. The analysis of terms, approaches to classifications of lectins is carried out. The features of natural and synthetic glycoconjugates, recognized and bound by lectins, in symbiotic relationships, in innate immunity at the reception level are emphasized. The levels of specificity of lectins are considered. There is a need to expand research on the glycoconjugate specificity of lectins and their systems, to assess the communication potential of glycoconjugates in relation to any protein combinations and systems as lectins. The participation of lectin and glycoconjugate systems in signal transmission and communication is noted. Lectins manifest themselves as basic for superstructure glycoconjugate effectors in soluble and solid cell phases in cascade directed assemblies forming the interactome network. Lectins and glycoconjugates, as inextricably co-functioning, are promising in biology, medicine and biotechnologies.

Publisher

The Russian Academy of Sciences

Reference25 articles.

1. Лахтин В.М. Лектины в исследовании белков и углеводов // Итоги науки и техники, серия Биотехнология. Т. 2. М.: ВИНИТИ, 1987. 288 с.

2. Лахтин В.М., Афанасьев С.С., Алешкин В.А. и др. Классификация лектинов как универсальных регуляторных молекул биологических систем // Вестник РАМН. 2009. № 3. С. 36–43.

3. Лахтин В.М., Лахтин М.В., Байракова А.Л. и др. Особенности метаболомбиотиков в сравнении с метабиотиками // Гастроэнтерология Санкт-Петербурга. 2022а. № 1–2. 20 с.

4. Лахтин В.М., Корсун В.Ф., Лахтин М.В. и др. Определение лектинов // Пробл. науч. мысли. 2023а. V. 2 (7). С. 18–29. ISSN 1561-6916. https://elibrary.ru/item.asp?id=54043566

5. Лахтин М.В., Лахтин В.М., Алешкин В.А. и др. Лектины и ферменты в биологии и медицине. М.: Династия, 2010. 496 с. ISBN 978-5-98125-076-7.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3