Suppression of the spiral wave in cardiac tissue by using forcing currents with diversity

Abstract

Forcing currents are generated by using two types of constant currents to stimulate different areas of a medium. The external current is mapped into transmembrane current and stable gradient force is induced to drive the stable rotating spiral wave. The medium becomes homogeneous when the spiral wave is removed and the time series of sampled membrane potentials becomes stable value without considering noise. The scheme is confirmed to be effective in the presence of Gaussian white noise.