Synthesis of Methyl 3-Azidothieno[2,3-b]pyridine-2-carboxylates and Application of the Huisgen Reaction-Reference-Cited by-同舟云学术

Synthesis of Methyl 3-Azidothieno[2,3-b]pyridine-2-carboxylates and Application of the Huisgen Reaction

Published:2014-05-01 Issue:5 Volume:69 Page:509-518
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:en
Short-container-title:

Author:

Chaouni Wafaâ¹²,Aadil Mina²,Djellal Ahmed¹³,Kirsch Gilbert¹

Affiliation:

1. SRMSC (LIMBP), UMR 7565 Institut Jean Barriol, Université de Lorraine, 1 Boulevard Arago, 57070 Metz, France

2. Laboratoire de Chimie Bioorganique et Analytique (LCBA), FST-Mohammedia, BP 146, 20800 Mohammedia, Maroc

3. Institut de Chimie, Faculté des Sciences, Université d’Annaba, 23000 Annaba, Algérie

Abstract

The preparation of new substituted methyl 3-azidothieno[2,3-b]pyridine carboxylates by azotization of methyl 3-aminothieno[2,3-b]pyridine and subsequent treatment with sodium azide is described. Via Huisgen’s 1,3-dipolar cycloaddition between substituted alkynes and the prepared azides, methyl 1,2,3-triazolo-thieno[2,3-b]pyridine carboxylates have been obtained.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.5560/znb.2014-3320/pdf

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