Rapid and Sensitive Detection of UGT1A1 Polymorphisms Associated with Irinotecan Toxicity by a Novel DNA Microarray
Author:
Affiliation:
1. Department of Gastroenterological, Breast and Endocrine Surgery（Surgery Ⅱ.），Yamaguchi University Graduate School of Medicine
Publisher
Yamaguchi University Medical Association
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/ymj/69/4/69_161/_pdf
Reference33 articles.
1. 1 Mathijssen RH, van Alphen RJ, Verweij J, et al. Clinical pharmacokinetics and metabolism of irinotecan（CPT-11）．Clin Cancer Res 2001；7：2182-94.
2. 2 Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer：a multicentre randomised trial. Lancet 2000；355：1041-7.
3. 3 Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000；343：905-14.
4. 4 Tournigand C, André T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer：a randomized GERCOR study. J Clin Oncol 2004；22：229-237.
5. 5 Pommier Y. Topoisomerase I inhibitors：camptothecins and beyond. Nat Rev Cancer 2006；6：789-802.
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