Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

Author:

Douillard JY,Cunningham D,Roth AD,Navarro M,James RD,Karasek P,Jandik P,Iveson T,Carmichael J,Alakl M,Gruia G,Awad L,Rougier P

Publisher

Elsevier BV

Subject

General Medicine

Reference24 articles.

1. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project.

2. Effective biomodulation by leucovorin of high-dose infusion fluorouracil given as a weekly 24-hour infusion: results of a randomised trial in patients with advanced colorectal cancer;Kohne;J Clin Oncol,1998

3. Tumour response and stabilization rates are worthwhile surrogate endpoints in metastatic colorectal cancer: analysis of data in 455 fluorouracil-resistant patients treated with irinotecan;Fages;Proc ASCO,1997

4. Quality of life during chemotherapy in patients with symptomatic advanced colorectal cancer;Glimelius;Cancer,1994

5. Clinical drug development: an analysis of phase II trials, 1970–1985;Marsoni;Cancer Treat Rep,1987

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