Affiliation:
1. Vladivostok Branch of Far Eastern Scientific Center for Physiology and Pathology of Respiration – Institute of Medical Climatology and Rehabilitation Therapy, Vladivostok, Russia
Abstract
The health risks associated with outdoor air pollution are of global concern. Atmospheric air pollution negatively affects a number of key aspects of human health, including the functioning of the respiratory, cardiovascular and central nervous systems, but many issues remain unresolved about the relationship between atmospheric air pollution and the development and course of pathologies. The review analyzes data from Russian and foreign sources on the effect of atmospheric particulate matter on the functional state of mitochondria. The effect of air pollution on structural changes in mitochondria, ATP synthesis, production of reactive oxygen species, damage to mitochondrial DNA, and mitochondrial membrane potential has been shown. The data presented in the review indicate the need for further studies of the functional state of mitochondria under the impact of solid particles in atmospheric air.
Publisher
LLC Science and Innovations
Reference64 articles.
1. Veremchuk LV, Yankova VI, Vitkina TI, Golohvast KS, Barskova LS. The atmospheric pollution in urbanized territories as a systemic process of the interaction among environmental factors. Health. Medical Ecology. Science 2015; (3): 35-42. Russian. https://www.elibrary.ru/item.asp?id=23754629.
2. Yu Y, Sun Q, Li T, Ren X, Lin L, Sun M, Duan J, Sun Z. Adverse outcome pathway of fine particulate matter leading to increased cardiovascular morbidity and mortality: An integrated perspective from toxicology and epidemiology. J Hazard Mater 2022; 430: 128368. https://doi.org/10.1016/j.jhazmat.2022.128368.
3. Chew S, Kolosowska N, Saveleva L, Malm T, Kanninen KM. Impairment of mitochondrial function by particulate matter: Implications for the brain. Neurochem Int 2020; 135: 104694. https://doi.org/10.1016/j.neuint.2020.104694.
4. Burnett R, Chen H, Szyszkowicz M, Fann N, Hubbell B, Pope CA 3rd, et al. Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter. Proc Natl Acad Sci USA 2018; 115(38): 9592-9597. https://doi.org/10.1073/pnas.1803222115.
5. Barskova LS, Vitkina TI, Gvozdenko TA, Veremchuk LV, Golokhvast KS. Assessment of air pollution by small-sized atmospheric particulate matter in urbanized territories with various technogenic load (On the example of Vladivostok, Russia). Russ Open Med J 2019; 8: e0304. https://doi.org/10.15275/rusomj.2019.0304.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献