Effects Of Atmospheric Suspended Particulate Matter On The Immune System

Author:

Kondratyeva Elena V.1ORCID,Vitkina Tatyana I.1ORCID

Affiliation:

1. Institute of Medical Climatology and Rehabilitative Treatment, Vladivostok Branch of the Far Eastern Scientific Center for Physiology and Pathology of Respiration, Vladivostok, Russia

Abstract

Atmospheric pollution causes enormous damage to public health worldwide resulting in millions of deaths annually, and reducing both life expectancy and quality of life. Suspended particulate matter (SPM) in the air triggers immune system responses, which in turn determines a wide range of diseases based on chronic inflammation. However, many issues regarding the relationship between air pollution and the development and course of pathologies remain unresolved. The present review summarizes the data of domestic and foreign publications regarding the effect of atmospheric SPM on the immune system. The article reveals the effect of SPM on immunocompetent cells and investigates cellular and molecular response mechanisms of the body. The data presented in the review imply the need for further studies of immune system response mechanisms under the impact of atmospheric SPM.

Publisher

LLC Science and Innovations

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