1. From the Department of Pharmacology and Pharmacotherapy, University of Amsterdam, Amsterdam, the Netherlands (MCM), Department of Nephrology, Klinikum rechts der Isar, Technical University, Munich (UH), Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim (HS, LM), and Department of Urology, Klinikum Niederberg, Velbert (MG), Germany