1. From the Tyne Micturition Research Group, School of Surgical Sciences, University of Newcastle, Newcastle, Oxford Continence Group, University Department of Pharmacology, Oxford, Department of Uroneurology, National Hospital for Neurology and Neurosurgery, and Department of Neuropathology, Institute of Neurology, Queen Square, London, United Kingdom, and Department of Clinical Pharmacology, Lund University Hospital, Lund, Sweden