Transfusion-related Acute Lung Injury in the Perioperative Patient

Author:

McVey Mark J.1,Kapur Rick1,Cserti-Gazdewich Christine1,Semple John W.1,Karkouti Keyvan1,Kuebler Wolfgang M.1

Affiliation:

1. From the Keenan Research Centre for Biomedical Science, St. Michael’s Hospital, Toronto, Canada (M.J.M., J.W.S., W.M.K); Departments of Physiology and Anesthesia (M.J.M.), Pharmacology (J.W.S.), Laboratory Medicine–Pathobiology (C.C.-G.), Medicine–Division of Hematology (C.C.-G.), Anesthesia and Pain Management, University Health Network (K.K.), and Physiology and Surgery (W.M.K.), University of

Abstract

Abstract Transfusion-related acute lung injury is a leading cause of death associated with the use of blood products. Transfusion-related acute lung injury is a diagnosis of exclusion which can be difficult to identify during surgery amid the various physiologic and pathophysiologic changes associated with the perioperative period. As anesthesiologists supervise delivery of a large portion of inpatient prescribed blood products, and since the incidence of transfusion-related acute lung injury in the perioperative patient is higher than in nonsurgical patients, anesthesiologists need to consider transfusion-related acute lung injury in the perioperative setting, identify at-risk patients, recognize early signs of transfusion-related acute lung injury, and have established strategies for its prevention and treatment.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Anesthesiology and Pain Medicine

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