One-Year Functional Outcomes After Invasive Mechanical Ventilation for Older Adults With Preexisting Long-Term Care-Needs*

Author:

Ohbe Hiroyuki1,Ouchi Kei2,Miyamoto Yuki3,Ishigami Yuichiro4,Matsui Hiroki1,Yasunaga Hideo1,Sasabuchi Yusuke5

Affiliation:

1. Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.

2. Department of Emergency Medicine, Brigham and Women’s Hospital, Boston, MA.

3. Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

4. Department of Transitional and Palliative Care, Aso Iizuka Hospital, Fukuoka, Japan.

5. Data Science Center, Jichi Medical University, Tochigi, Japan.

Abstract

OBJECTIVES: To examine 1-year functional outcomes after invasive mechanical ventilation for adults greater than or equal to 65 years with preexisting long-term care-needs. DESIGN: We used medical and long-term care administrative databases. The database included data on functional and cognitive impairments that were assessed with the national standardized care-needs certification system and were categorized into seven care-needs levels based on the total daily estimated care minutes. Primary outcome was mortality and care-needs at 1 year after invasive mechanical ventilation. Outcome was stratified by preexisting care-needs at the time of invasive mechanical ventilation: no care-needs, support level 1–2 and care-needs level 1 (estimated care time 25–49 min), care-needs level 2–3 (50–89 min), and care-needs level 4–5 (≥90 min). SETTING: A population-based cohort study in Tochigi Prefecture, one of 47 prefectures in Japan. PATIENTS: Among people greater than or equal to 65 years old registered between June 2014 and February 2018, patients who received invasive mechanical ventilation were identified. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among 593,990 eligible people, 4,198 (0.7%) received invasive mechanical ventilation. The mean age was 81.2 years, and 55.5% were male. The 1-year mortality rates after invasive mechanical ventilation in patients with no care-needs, support level 1–2 and care-needs level 1, care-needs level 2–3, and care-needs level 4–5 at the time of invasive mechanical ventilation were 43.4%, 54.9%, 67.8%, and 74.1%, respectively. Similarly, those with worsened care-needs were 22.8%, 24.2%, 11.4%, and 1.9%, respectively. CONCLUSIONS: Among patients in preexisting care-needs levels 2–5 who received invasive mechanical ventilation, 76.0–79.2% died or had worsened care-needs within 1 year. These findings may aid shared decision-making among patients, their families, and heath care professionals on the appropriateness of starting invasive mechanical ventilation for people with poor functional and cognitive status at baseline.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Critical Care and Intensive Care Medicine

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