Genetic regulation of dihydropyrimidinase and its possible implication in altered uracil catabolism

Author:

Thomas Holly R.,Ezzeldin Hany H.,Guarcello Vincenzo,Mattison Lori K.,Fridley Brooke L.,Diasio Robert B.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference36 articles.

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2. Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors;J Clin Oncol,1998

3. Clinical pharmacokinetics of 5-fluorouracil and its metabolism in plasma, urine, and bile;Heggie;Cancer Res,1987

4. Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil;Johnson;Adv Enzyme Regul,2001

5. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution;Hamajima;Gene,1996

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