Short-Term Immunosuppression Facilitates Induction of Mixed Chimerism and Tolerance after Bone Marrow Transplantation without Cytoreductive Conditioning
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Transplantation
Reference23 articles.
1. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance.;Wekerle;J Exp Med,1998
2. Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression.;Adams;J Immunol,2001
3. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway.;Ito;J Immunol,2001
4. Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions.;Taylor;Blood,2001
5. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment.;Wekerle;Nat Med,2000
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1. Combining Treg Therapy With Donor Bone Marrow Transplantation: Experimental Progress and Clinical Perspective;Transplantation;2023-10-04
2. Chimerism, Transplant Tolerance, and Beyond;Transplantation;2019-08
3. Stability of Chimerism in Non-Obese Diabetic Mice Achieved By Rapid T Cell Depletion Is Associated With High Levels of Donor Cells Very Early After Transplant;Frontiers in Immunology;2018-04-24
4. Transplantation Tolerance through Hematopoietic Chimerism: Progress and Challenges for Clinical Translation;Frontiers in Immunology;2017-12-22
5. Murine models of transplantation tolerance through mixed chimerism: advances and roadblocks;Clinical and Experimental Immunology;2017-05-22
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