Pharmacokinetics of Diltiazem and Its Metabolites After Single and Multiple Dosing in Healthy Volunteers
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Pharmacology (medical),Pharmacology
Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Weight-based versus non-weight-based diltiazem dosing in the setting of atrial fibrillation with rapid ventricular response;The American Journal of Emergency Medicine;2020-11
2. Use of Human Plasma Samples to Identify Circulating Drug Metabolites that Inhibit Cytochrome P450 Enzymes;Drug Metabolism and Disposition;2016-06-06
3. Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme;Drug Metabolism and Disposition;2012-04-19
4. Physiologically-Based Pharmacokinetics;Biosimulation in Biomedical Research, Health Care and Drug Development;2011
5. Physiologically based mechanistic modelling to predict complex drug–drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut—The effect of diltiazem on the time-course of exposure to triazolam;European Journal of Pharmaceutical Sciences;2010-03
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