Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair

Author:

Myles Ian A.12ORCID,Castillo Carlo R.12ORCID,Barbian Kent D.3ORCID,Kanakabandi Kishore3ORCID,Virtaneva Kimmo3ORCID,Fitzmeyer Emily3ORCID,Paneru Monica3,Otaizo-Carrasquero Francisco4ORCID,Myers Timothy G.4ORCID,Markowitz Tovah E.56,Moore Ian N.7ORCID,Liu Xue8ORCID,Ferrer Marc8,Sakamachi Yosuke9,Garantziotis Stavros9ORCID,Swamydas Muthulekha10ORCID,Lionakis Michail S.10,Anderson Erik D.2ORCID,Earland Noah J.2ORCID,Ganesan Sundar11,Sun Ashleigh A.2ORCID,Bergerson Jenna R.E.2,Silverman Robert A.12ORCID,Petersen Maureen13ORCID,Martens Craig A.3,Datta Sandip K.2ORCID

Affiliation:

1. Epithelial Therapeutics Unit, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.

2. Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.

3. RTS Genomics Unit, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA.

4. Genomic Technologies Section, NIAID, NIH, Bethesda, MD, USA.

5. NIAID Collaborative Bioinformatics Resource (NCBR), NIAID, NIH, Bethesda, MD, USA.

6. Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.

7. Infectious Disease Pathogenesis Section, Comparative Medicine Branch, NIAID, NIH, Rockville, MD, USA.

8. Department of Pre-clinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA.

9. National Institute of Environmental Health Sciences, Research Triangle, NC, USA.

10. Fungal Pathogenesis Section, LCIM, NIAID, NIH, Bethesda, MD, USA.

11. Biological Imaging Section, Research Technology Branch, NIAID, NIH, Bethesda, MD, USA.

12. Department of Pediatrics, Georgetown University Hospital, Washington, DC, USA.

13. Walter Reed National Military Medical Center, Bethesda, MD, USA.

Abstract

Roseomonas mucosa treatment in children with atopic dermatitis is associated with clinical improvements and potentially lipid-mediated TNF signaling.

Funder

National Institutes of Health

National Institute of Environmental Health Sciences

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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