Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival-Reference-Cited by-同舟云学术

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Published:2016-02-03 Issue:324 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Yang Guangrui¹,Chen Lihong¹,Grant Gregory R.¹²,Paschos Georgios¹,Song Wen-Liang¹,Musiek Erik S.³,Lee Vivian⁴,McLoughlin Sarah C.¹,Grosser Tilo¹,Cotsarelis George⁵,FitzGerald Garret A.¹

Affiliation:

1. The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

2. Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.

3. Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.

4. Department of Ophthalmology, University of Pennsylvania Scheie Eye Institute, Philadelphia, PA 19104, USA.

5. Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA.

Abstract

Postnatal knockout of a core clock gene in mice prompts reevaluation of the systemic role of the molecular clock in the biology of aging.

Funder

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference36 articles.

1. Molecular Bases of Circadian Rhythms

2. The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

3. Effects of circadian disruption on the cardiometabolic system

4. Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice

5. Progressive arthropathy in mice with a targeted disruption of theMop3/Bmal-1 locus

Cited by 248 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hypertension disrupts the vascular clock in both sexes;American Journal of Physiology-Heart and Circulatory Physiology;2024-10-01

2. A coupled model between circadian, cell-cycle, and redox rhythms reveals their regulation of oxidative stress;Scientific Reports;2024-07-05

3. Feeding behavior modifies the circadian variation in RR and QT intervals by distinct mechanisms in mice;American Journal of Physiology-Regulatory, Integrative and Comparative Physiology;2024-07-01

4. BMAL1 sex‐specific effects in the neonatal mouse airway exposed to moderate hyperoxia;Physiological Reports;2024-06-28

5. BMAL1 represses transposable elements independently of CLOCK in pluripotent cells;2024-06-18