Endogenous retroviruses in ALS: A reawakening?-Reference-Cited by-同舟云学术

Endogenous retroviruses in ALS: A reawakening?

Published:2015-09-30 Issue:307 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Brown Robert H.¹,Al-Chalabi Ammar²

Affiliation:

1. University of Massachusetts Medical School, Worcester, MA 01655, USA.

2. Wohl Clinical Neuroscience Institute, King’s College London and NIHR Dementia Biomedical Research Unit, London SE5 9RX, UK.

Abstract

New data incriminate the human endogenous retrovirus HERV-K in the pathogenesis of ALS and document that the HERV-K envelope protein can be neurotoxic (Li et al ., this issue).

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference10 articles.

1. Emerging mechanisms of molecular pathology in ALS

2. Human endogenous retrovirus-K contributes to motor neuron disease

3. Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

4. A. B. Rabson B. J. Graves in Retroviruses J. M. Coffin S. H. Hughes H. E. Varmus Eds. (Cold Spring Harbor Laboratory Press Cold Spring Harbor NY 1997) pp. 205–262.

5. Age-dependent poliomyelitis of mice: expression of endogenous retrovirus correlates with cytocidal replication of lactate dehydrogenase-elevating virus in motor neurons

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