A once-a-month oral contraceptive

Author:

Kirtane Ameya R.12ORCID,Hua Tiffany12,Hayward Alison123ORCID,Bajpayee Ambika4,Wahane Aniket12,Lopes Aaron12,Bensel Taylor12,Ma Lihong5,Stanczyk Frank Z.5,Brooks Sierra1,Gwynne Declan12,Wainer Jacob12,Collins Joy12ORCID,Tamang Siddartha M.12ORCID,Langer Robert12678ORCID,Traverso Giovanni89ORCID

Affiliation:

1. David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

4. Departments of Bioengineering and Mechanical Engineering, Northeastern University, Boston, MA 02115, USA.

5. Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

6. Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

7. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

8. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

9. Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

Abstract

An oral dosage form that resides in the stomach releases the contraceptive levonorgestrel over 1 month in pigs.

Funder

Bill and Melinda Gates Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference31 articles.

1. World Health Organization “Family planning/contraception ” (2018); www.who.int/news-room/fact-sheets/detail/family-planning-contraception.

2. Unintended pregnancy in the United States: incidence and disparities, 2006

3. Contraception in women over 40 years of age

4. Centers Disease Control and Prevention “Contraception ” (2018); www.cdc.gov/reproductivehealth/contraception/index.htm.

5. United States Food and Drug Administration Nexplanon FDA label (2015); www.accessdata.fda.gov/drugsatfda_docs/label/2015/021529s011lbl.pdf.

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