Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo

Author:

Adams David C.12,Hariri Lida P.23,Miller Alyssa J.1,Wang Yan12,Cho Josalyn L.14,Villiger Martin2,Holz Jasmin A.12,Szabari Margit V.12,Hamilos Daniel L.4,Scott Harris R.1,Griffith Jason W.14,Bouma Brett E.2,Luster Andrew D.4,Medoff Benjamin D.14,Suter Melissa J.12

Affiliation:

1. Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

2. Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

3. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

4. Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

A birefringence microscopy technique provides structural and functional information about airway smooth muscle in healthy and mild asthmatic subjects.

Funder

Boston Scientific Corporation

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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