MG53-mediated cell membrane repair protects against acute kidney injury-Reference-Cited by-同舟云学术

MG53-mediated cell membrane repair protects against acute kidney injury

Published:2015-03-18 Issue:279 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Duann Pu¹,Li Haichang¹,Lin Peihui¹,Tan Tao¹,Wang Zhen²,Chen Ken²,Zhou Xinyu¹,Gumpper Kristyn¹,Zhu Hua¹,Ludwig Thomas³,Mohler Peter J.⁴⁵,Rovin Brad⁵,Abraham William T.⁵,Zeng Chunyu²,Ma Jianjie¹³

Affiliation:

1. Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

2. Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing Institute of Cardiology, Chongqing 400042, China.

3. Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

4. Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

5. Department of Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

Abstract

Recombinant MG53 translocates to sites of injury in the proximal tubule of the kidney and protects mice from acute kidney injury induced by ischemia or drugs.

Funder

NIH

American Heart Association Scientist Development

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference54 articles.

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5. Linkermann A., Chen G., Dong G., Kunzendorf U., Krautwald S., Dong Z., Regulated cell death in AKI. J. Am. Soc. Nephrol. 25, 2689–2701 (2014).

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