Response to comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI”-Reference-Cited by-同舟云学术

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Response to comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI”

Published:2021-05-12 Issue:593 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Yu Xiaowen¹²³^ORCID,Zhang Yue¹²³^ORCID,Jia Zhanjun¹²³^ORCID,Zhang Aihua¹²³^ORCID

Affiliation:

1. Department of Nephrology, Children’s Hospital of Nanjing Medical University, Nanjing 210008, China.

2. Nanjing Key Laboratory of Pediatrics, Children’s Hospital of Nanjing Medical University, Nanjing 210008, China.

3. Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing 210029, China.

Abstract

The nuclear pregnane X receptor protects against bilateral renal ischemia/reperfusion-induced acute kidney injury in mice.

Funder

Government of Jiangsu Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference8 articles.

1. Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI

2. Comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI”

3. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

4. SXR, a novel steroid and xenobioticsensing nuclear receptor

5. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

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