A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

Author:

Templeman Iain1ORCID,Smith Harry Alex1ORCID,Chowdhury Enhad1ORCID,Chen Yung-Chih12ORCID,Carroll Harriet13ORCID,Johnson-Bonson Drusus1,Hengist Aaron1,Smith Rowan1ORCID,Creighton Jade14ORCID,Clayton David4ORCID,Varley Ian4ORCID,Karagounis Leonidas Georgios56ORCID,Wilhelmsen Andrew7ORCID,Tsintzas Kostas7,Reeves Sue8ORCID,Walhin Jean-Philippe1ORCID,Gonzalez Javier Thomas1ORCID,Thompson Dylan1,Betts James Alexander1ORCID

Affiliation:

1. Centre for Nutrition, Exercise and Metabolism, Department for Health, University of Bath, Bath BA2 7AY, UK.

2. Department of Physical Education, National Taiwan Normal University, Taipei City 106, Taiwan.

3. Cardiovascular Research–Hypertension, Clinical Research Centre, Lund University, Malmö 221 00, Sweden.

4. School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.

5. Nestlé Health Science, Translation Research, Avenue Nestlé 55, CH-1800 Vevey, Switzerland.

6. Institute of Social and Preventive Medicine, University of Bern, 3012 Bern, Switzerland.

7. MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK.

8. Department of Life Sciences, University of Roehampton, London SW15 4JD, UK.

Abstract

Daily energy restriction more effectively reduces body fat content than alternate-day fasting, with no evidence of fasting-specific health benefits.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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