High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy-Reference-Cited by-同舟云学术

High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy

Published:2014-02-05 Issue:222 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ma Yan¹²,Chapman Julia³,Levine Mark⁴,Polireddy Kishore¹²,Drisko Jeanne²,Chen Qi¹²

Affiliation:

1. Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.

2. KU Integrative Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.

3. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

4. National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Abstract

Pharmacological use of ascorbate (vitamin C) enhanced chemosensitivity of ovarian cancer in preclinical models and reduced chemotherapy-associated toxicity in patients.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference57 articles.

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2. Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects

3. Cancer: The preconditioning factor in pathogenesis; a new etiologic approach.;McCormick W. J.;Arch. Pediatr.,1954

4. ASCORBIC ACID, CELL PROLIFERATION, AND CANCER

5. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

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