Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates-Reference-Cited by-同舟云学术

Safety and Antithrombotic Efficacy of Moderate Platelet Count Reduction by Thrombopoietin Inhibition in Primates

Published:2010-06-23 Issue:37 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Tucker Erik I.¹,Marzec Ulla M.¹,Berny Michelle A.¹,Hurst Sawan¹,Bunting Stuart²,McCarty Owen J. T.¹,Gruber András¹³,Hanson Stephen R.¹³

Affiliation:

1. Department of Biomedical Engineering, Oregon Health & Science University School of Medicine, 3303 Southwest Bond Avenue, CH13B, Portland, OR 97239, USA.

2. BioMarin Inc., Novato, CA 94949, USA.

3. Oregon National Primate Research Center, Beaverton, OR 97006, USA.

Abstract

Inhibition of platelet production safely reduces blood clot formation without increasing bleeding side effects in baboons.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference57 articles.

1. Platelets in atherothrombosis

2. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

3. Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events

4. Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes

5. Comparison of Two Platelet Glycoprotein IIb/IIIa Inhibitors, Tirofiban and Abciximab, for the Prevention of Ischemic Events with Percutaneous Coronary Revascularization

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