Induction of ICOS + CXCR3 + CXCR5 + T H Cells Correlates with Antibody Responses to Influenza Vaccination

Author:

Bentebibel Salah-Eddine12,Lopez Santiago3,Obermoser Gerlinde1,Schmitt Nathalie1,Mueller Cynthia1,Harrod Carson12,Flano Emilio3,Mejias Asuncion3,Albrecht Randy A.45,Blankenship Derek1,Xu Hui1,Pascual Virginia12,Banchereau Jacques1,Garcia-Sastre Adolfo456,Palucka Anna Karolina12,Ramilo Octavio3,Ueno Hideki12

Affiliation:

1. Baylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.

2. Institute of Biomedical Studies, Baylor University, Waco, TX 76798, USA.

3. The Research Institute at Nationwide Children’s Hospital, Columbus, OH 43205, USA.

4. Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA.

5. Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.

6. Division of Infectious Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.

Abstract

A T cell subset that emerges in blood after seasonal influenza vaccinations correlates with the development of protective antibody responses.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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