NCR3/NKp30 Contributes to Pathogenesis in Primary Sjögren’s Syndrome

Author:

Rusakiewicz Sylvie123,Nocturne Gaetane34,Lazure Thierry5,Semeraro Michaela26,Flament Caroline12,Caillat-Zucman Sophie78,Sène Damien789,Delahaye Nicolas1,Vivier Eric1011,Chaba Kariman112,Poirier-Colame Vichnou12,Nordmark Gunnel13,Eloranta Maija-Leena13,Eriksson Per14,Theander Elke15,Forsblad-d’Elia Helena16,Omdal Roald17,Wahren-Herlenius Marie18,Jonsson Roland19,Rönnblom Lars13,Nititham Joanne20,Taylor Kimberly E.20,Lessard Christopher J.21,Sivils Kathy L. Moser21,Gottenberg Jacques-Eric22,Criswell Lindsey A.20,Miceli-Richard Corinne123,Zitvogel Laurence1234,Mariette Xavier3423

Affiliation:

1. INSERM U1015, Institut Gustave Roussy (IGR), 94805 Villejuif, France.

2. Center of Clinical Investigations, CICBT507, IGR, 94805 Villejuif, France.

3. Faculté de Médecine Université Paris-Sud, 94276 Le Kremlin Bicêtre, France.

4. INSERM U1012, Université Paris-Sud, 94276 Le Kremlin Bicêtre, France.

5. Department of Pathology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Paris-Sud, 94275 Le Kremlin Bicêtre, France.

6. Department of Oncological Pediatrics, IGR, 94805 Villejuif, France.

7. INSERM U986, Hôpital St-Vincent de Paul, 75014 Paris, France.

8. Université Paris Diderot, 75013 Paris, France.

9. Department of Internal Medicine, AP-HP, Groupe Hospitalier Lariboisière, 75010 Paris, France.

10. Centre d’Immunologie de Marseille-Luminy, INSERM, U1104, F-13009 Marseille, France.

11. CNRS, UMR7280, 13288 Marseille, France.

12. Université Paris Descartes, 75006 Paris, France.

13. Rheumatology, Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.

14. Rheumatology AIR, Department of Clinical and Experimental Medicine, Linköping University, SE-581 83 Linköping, Sweden.

15. Skane University Hospital, Lund University, SE-205 02 Malmö, Sweden.

16. Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, S-405 30 Gothenburg, Sweden.

17. Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, 4068 Stavanger, Norway.

18. Rheumatology Unit, Department of Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

19. Broegelmann Research Laboratory, the Gade Institute, University of Bergen, NO-5020 Bergen, Norway.

20. Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, San Francisco, CA 94117, USA.

21. Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

22. Department of Rheumatology, EA 4438, Strasbourg University Hospital, Hôpital Hautepierre, 67000 Strasbourg, France.

23. Department of Rheumatology, AP-HP, Hôpitaux Universitaires Paris-Sud, 94275 Le Kremlin Bicêtre, France.

Abstract

Genetic and functional analyses implicate NCR3/NKp30 in the pathogenesis of primary Sjögren’s syndrome.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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