The Demographic and Biomedical Case for Late-Life Interventions in Aging

Author:

Rae Michael J.1,Butler Robert N.2,Campisi Judith3,de Grey Aubrey D. N. J.1,Finch Caleb E.4,Gough Michael5,Martin George M.6,Vijg Jan7,Perrott Kevin M.8,Logan Barbara J.8

Affiliation:

1. Strategies for Engineered Negligible Senescence (SENS) Foundation, Sunnyvale, CA 94089, USA.

2. International Longevity Center, New York, NY 10028, USA.

3. Buck Institute for Age Research, Novato, CA 94545, USA.

4. Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089, USA.

5. Retired; formerly Office of Technology Assessment, U.S. Congress, Washington, DC.

6. Departments of Pathology and Genome Sciences, University of Washington, Seattle, WA 98195, USA.

7. Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

8. LifeStar Institute, Orlando, FL 32819, USA.

Abstract

A global research agenda to slow or arrest the effects of biological aging has the potential to avert enormous economic, social, and human costs.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference34 articles.

1. A standard procedure for creating a frailty index

2. Does Damage to DNA and Other Macromolecules Play a Role in Aging? If So, How?

3. C. E. Finch The Biology of Human Longevity. Inflammation Nutrition and Aging in the Evolution of Lifespans (Academic Press Burlington MA 2007).

4. R. Weindruch R. L. Walford The Retardation of Aging and Disease by Dietary Restriction (Charles C. Thomas Springfield IL 1988).

5. The Plasticity of Aging: Insights from Long-Lived Mutants

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