Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species-Reference-Cited by-同舟云学术

Vaccine Vectors Derived from a Large Collection of Simian Adenoviruses Induce Potent Cellular Immunity Across Multiple Species

Published:2012-01-04 Issue:115 Volume:4 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Colloca Stefano¹,Barnes Eleanor²³,Folgori Antonella¹,Ammendola Virginia¹,Capone Stefania¹,Cirillo Agostino⁴,Siani Loredana¹,Naddeo Mariarosaria¹,Grazioli Fabiana¹,Esposito Maria Luisa¹,Ambrosio Maria¹,Sparacino Angela¹,Bartiromo Marta¹,Meola Annalisa⁴,Smith Kira²,Kurioka Ayako²,O’Hara Geraldine A.⁵,Ewer Katie J.⁵,Anagnostou Nicholas⁵,Bliss Carly⁵,Hill Adrian V. S.⁵,Traboni Cinzia¹,Klenerman Paul²,Cortese Riccardo¹⁶,Nicosia Alfredo¹⁶

Affiliation:

1. Okairos, via dei Castelli Romani 22, 00040 Pomezia (Rome), Italy.

2. Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK.

3. National Institute for Health and Research Biomedical Research Centre and Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK.

4. Istituto di Ricerche di Biologia Molecolare “P. Angeletti,” via Pontina km 30.600, 00040 Pomezia (Rome), Italy.

5. The Jenner Institute, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.

6. CEINGE, via Gaetano Salvatore 486, 80145 Naples, Italy.

Abstract

Simian adenoviruses screened from wild-derived candidates can prime T cell responses in man and may serve as new vaccine vector candidates.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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